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Are T(regs) defective in Type 1 Diabetes and can we fix them?

Regulatory T cells (T(regs)) are critical regulators of peripheral immune tolerance. T(reg) insufficiency can lead to autoimmune disorders, including Type 1 Diabetes (T1D). Increasing evidence in mouse models of T1D, as well as other autoimmune disorders, suggest that there are defects in T(reg)-med...

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Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Visperas, Anabelle, Vignali, Dario A.A.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119643/
https://ncbi.nlm.nih.gov/pubmed/27815439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601118
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