Selective reduction of IFN-γ single positive mycobacteria-specific CD4+ T cells in HIV-1 infected individuals with latent tuberculosis infection

HIV-1 is recognized to increase the risk for tuberculosis even before CD4+ T cell deficiency is profound. To better understand how HIV-1 alters immunity to latent tuberculosis, we compared the magnitude and functional profile of mycobacteria-specific CD4+ T cells between HIV-uninfected and HIV-infec...

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Publicado no:Tuberculosis (Edinb)
Main Authors: Riou, Catherine, Bunjun, Rubina, Müller, Tracey L., Kiravu, Agano, Ginbot, Zekarias, Oni, Tolu, Goliath, Rene, Wilkinson, Robert J., Burgers, Wendy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Churchill Livingstone 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119638/
https://ncbi.nlm.nih.gov/pubmed/27865393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2016.07.018
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