Functional neutralization of anti-IFN-γ autoantibody in patients with nontuberculous mycobacteria infection

Interferon (IFN)-γ is crucial for normal immune surveillance and exhibits immunomodulatory, antimicrobial, and anticancer activity. Patients with nontuberculous mycobacteria (NTM) infection commonly express high levels of anti-IFN-γ autoantibodies (autoAbs) and suffer from recurrent infections due t...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Krisnawati, Dyah Ika, Liu, Yung-Ching, Lee, Yuarn-Jang, Wang, Yun-Ting, Chen, Chia-Ling, Tseng, Po-Chun, Lin, Chiou-Feng
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450904/
https://ncbi.nlm.nih.gov/pubmed/30952894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41952-1
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