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New Aspercryptins, Lipopeptide Natural Products, Revealed by HDAC Inhibition in Aspergillus nidulans

Unlocking the biochemical stores of fungi is key for developing future pharmaceuticals. Through reduced expression of a critical histone deacetylase in Aspergillus nidulans, increases of up to 100-fold were observed in the levels of 15 new aspercryptins, recently described lipopeptides with two non-...

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Detaylı Bibliyografya
Yayımlandı:ACS Chem Biol
Asıl Yazarlar: Henke, Matthew T., Soukup, Alexandra A., Goering, Anthony W., McClure, Ryan A., Thomson, Regan J., Keller, Nancy P., Kelleher, Neil L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119465/
https://ncbi.nlm.nih.gov/pubmed/27310134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00398
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