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Development of Genetic Dereplication Strains in Aspergillus nidulans Results in the Discovery of Aspercryptin()
To reduce the secondary metabolite background in Aspergillus nidulans and minimize the rediscovery of compounds and pathway intermediates, we have created a “genetic dereplication” strain in which we have deleted eight of the most highly expressed secondary metabolite gene clusters (more than 244,00...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4724294/ https://ncbi.nlm.nih.gov/pubmed/26563584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201507097 |
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