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eis Promoter C14G and C15G Mutations Do Not Confer Kanamycin Resistance in Mycobacterium tuberculosis

We studied the significance of particular eis mutations on Mycobacterium tuberculosis drug resistance using a specialized transduction strategy. Recombinant strains harboring eis promoter mutations C14T, C12T, and G10A exhibited kanamycin resistance with MICs of 40, 10, and 20 μg/ml, respectively, w...

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Foilsithe in:Antimicrob Agents Chemother
Main Authors: Pholwat, Suporn, Stroup, Suzanne, Heysell, Scott, Ogarkov, Oleg, Zhdanova, Svetlana, Ramakrishnan, Girija, Houpt, Eric
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2016
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119041/
https://ncbi.nlm.nih.gov/pubmed/27736762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01775-16
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