Pharmacokinetic Interactions between Tafenoquine and Dihydroartemisinin-Piperaquine or Artemether-Lumefantrine in Healthy Adult Subjects

Tafenoquine is in development as a single-dose treatment for relapse prevention in individuals with Plasmodium vivax malaria. Tafenoquine must be coadministered with a blood schizonticide, either chloroquine or artemisinin-based combination therapy (ACT). This open-label, randomized, parallel-group...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Green, Justin A., Mohamed, Khadeeja, Goyal, Navin, Bouhired, Samia, Hussaini, Azra, Jones, Siôn W., Koh, Gavin C. K. W., Kostov, Ivan, Taylor, Maxine, Wolstenholm, Allen, Duparc, Stephan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Clinical Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119013/
https://ncbi.nlm.nih.gov/pubmed/27697758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01588-16
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