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Cytochrome P450 Organization and Function Are Modulated by Endoplasmic Reticulum Phospholipid Heterogeneity

Cytochrome P450s (P450s) comprise a superfamily of proteins that catalyze numerous monooxygenase reactions in animals, plants, and bacteria. In eukaryotic organisms, these proteins not only carry out reactions necessary for the metabolism of endogenous compounds, but they are also important in the o...

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Publicado en:Drug Metab Dispos
Autores principales: Brignac-Huber, Lauren M., Park, Ji Won, Reed, James R., Backes, Wayne L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118634/
https://ncbi.nlm.nih.gov/pubmed/27233287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.068981
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