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Organization of NADPH-Cytochrome P450 Reductase and CYP1A2 in the Endoplasmic Reticulum—Microdomain Localization Affects Monooxygenase Function

Cytochrome P450 is part of an electron transport chain found in the endoplasmic reticulum (ER), with its catalytic function requiring interactions with NADPH-cytochrome P450 reductase (CPR). The goals of this study were to examine how the P450 system proteins are organized in the membrane and to det...

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Detalhes bibliográficos
Main Authors: Brignac-Huber, Lauren, Reed, James R., Backes, Wayne L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061359/
https://ncbi.nlm.nih.gov/pubmed/21156755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.068817
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