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Organization of NADPH-Cytochrome P450 Reductase and CYP1A2 in the Endoplasmic Reticulum—Microdomain Localization Affects Monooxygenase Function

Cytochrome P450 is part of an electron transport chain found in the endoplasmic reticulum (ER), with its catalytic function requiring interactions with NADPH-cytochrome P450 reductase (CPR). The goals of this study were to examine how the P450 system proteins are organized in the membrane and to det...

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Main Authors: Brignac-Huber, Lauren, Reed, James R., Backes, Wayne L.
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Pharmacology and Experimental Therapeutics 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061359/
https://ncbi.nlm.nih.gov/pubmed/21156755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.068817
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