ROS-Responsive Mitochondria-Targeting Blended Nanoparticles: Chemo- and Photodynamic Synergistic Therapy for Lung Cancer with On-Demand Drug Release upon Irradiation with a Single Light Source

Mitochondria in cancer cells maintain a more negative membrane potential than normal cells. Mitochondria are the primary source of cellular reactive oxygen species (ROS), which are necessary for photodynamic therapy. Thus, the strategy of targeting mitochondria can maximize the photodynamic therapeu...

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Enregistré dans:
Détails bibliographiques
Publié dans:Theranostics
Auteurs principaux: Yue, Caixia, Yang, Yuming, Zhang, Chunlei, Alfranca, Gabriel, Cheng, Shangli, Ma, Lijun, Liu, Yanlei, Zhi, Xiao, Ni, Jian, Jiang, Weihua, Song, Jie, de la Fuente, Jesús M., Cui, Daxiang
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118600/
https://ncbi.nlm.nih.gov/pubmed/27877240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.15433
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