ROS-Responsive Mitochondria-Targeting Blended Nanoparticles: Chemo- and Photodynamic Synergistic Therapy for Lung Cancer with On-Demand Drug Release upon Irradiation with a Single Light Source

Mitochondria in cancer cells maintain a more negative membrane potential than normal cells. Mitochondria are the primary source of cellular reactive oxygen species (ROS), which are necessary for photodynamic therapy. Thus, the strategy of targeting mitochondria can maximize the photodynamic therapeu...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Yue, Caixia, Yang, Yuming, Zhang, Chunlei, Alfranca, Gabriel, Cheng, Shangli, Ma, Lijun, Liu, Yanlei, Zhi, Xiao, Ni, Jian, Jiang, Weihua, Song, Jie, de la Fuente, Jesús M., Cui, Daxiang
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118600/
https://ncbi.nlm.nih.gov/pubmed/27877240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.15433
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