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Cl-out is a novel cooperative optogenetic tool for extruding chloride from neurons

Chloride regulation affects brain function in many ways, for instance, by dictating the GABAergic reversal potential, and thereby influencing neuronal excitability and spike timing. Consistent with this, there is increasing evidence implicating chloride in a range of neurological conditions. Investi...

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Udgivet i:Nat Commun
Main Authors: Alfonsa, Hannah, Lakey, Jeremy H., Lightowlers, Robert N., Trevelyan, Andrew J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118542/
https://ncbi.nlm.nih.gov/pubmed/27853135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13495
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