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Cl-out is a novel cooperative optogenetic tool for extruding chloride from neurons

Chloride regulation affects brain function in many ways, for instance, by dictating the GABAergic reversal potential, and thereby influencing neuronal excitability and spike timing. Consistent with this, there is increasing evidence implicating chloride in a range of neurological conditions. Investi...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Alfonsa, Hannah, Lakey, Jeremy H., Lightowlers, Robert N., Trevelyan, Andrew J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118542/
https://ncbi.nlm.nih.gov/pubmed/27853135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13495
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