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A FANCD2/FANCI-Associated Nuclease 1-Knockout Model Develops Karyomegalic Interstitial Nephritis

Karyomegalic interstitial nephritis (KIN) is a chronic interstitial nephropathy characterized by tubulointerstitial nephritis and formation of enlarged nuclei in the kidneys and other tissues. We recently reported that recessive mutations in the gene encoding FANCD2/FANCI-associated nuclease 1 (FAN1...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Airik, Rannar, Schueler, Markus, Airik, Merlin, Cho, Jang, Porath, Jonathan D., Mukherjee, Elina, Sims-Lucas, Sunder, Hildebrandt, Friedhelm
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118483/
https://ncbi.nlm.nih.gov/pubmed/27026368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015101108
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