Aberrant DNA methylation of alternative promoter of DLC1 isoform 1 in meningiomas

DLC1 encodes GTPase-activating protein with a well-documented tumor suppressor activity. This gene is downregulated in various tumors through aberrant promoter hypermethylation. Five different DLC1 isoforms can be transcribed from alternative promoters. Tumor-related DNA methylation of the DLC1 isof...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurooncol
Prif Awduron: Bujko, M., Kober, P., Rusetska, N., Wakuła, M., Goryca, K., Grecka, E., Matyja, E., Neska, J., Mandat, T., Bonicki, W., Siedlecki, J. A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer US 2016
Pynciau:
Laboratory Investigation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118400/
https://ncbi.nlm.nih.gov/pubmed/27614886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-016-2261-3
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg