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Aberrant DNA methylation of alternative promoter of DLC1 isoform 1 in meningiomas
DLC1 encodes GTPase-activating protein with a well-documented tumor suppressor activity. This gene is downregulated in various tumors through aberrant promoter hypermethylation. Five different DLC1 isoforms can be transcribed from alternative promoters. Tumor-related DNA methylation of the DLC1 isof...
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| Publicado no: | J Neurooncol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5118400/ https://ncbi.nlm.nih.gov/pubmed/27614886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-016-2261-3 |
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