Simvastatin Rapidly and Reversibly Inhibits Insulin Secretion in Intact Single-Islet Cultures

INTRODUCTION: Epidemiological studies suggest that statins may promote the development or exacerbation of diabetes, but whether this occurs through inhibition of insulin secretion is unclear. This lack of understanding is partly due to the cellular models used to explore this phenomenon (cell lines...

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Bibliografske podrobnosti
izdano v:Diabetes Ther
Main Authors: Scattolini, Valentina, Luni, Camilla, Zambon, Alessandro, Galvanin, Silvia, Gagliano, Onelia, Ciubotaru, Catalin Dacian, Avogaro, Angelo, Mammano, Fabio, Elvassore, Nicola, Fadini, Gian Paolo
Format: Artigo
Jezik:Inglês
Izdano: Springer Healthcare 2016
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118248/
https://ncbi.nlm.nih.gov/pubmed/27830474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13300-016-0210-y
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