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Small-angle x-ray scattering of calpain-5 reveals a highly open conformation among calpains
Calpain-5 is a calcium-activated protease expressed in the retina. Mutations in calpain-5 cause autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV, OMIM#193235). The structure of calpain-5 has not been determined, thus hindering the investigation of its proteolytic targets and path...
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| Publicado no: | J Struct Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5118095/ https://ncbi.nlm.nih.gov/pubmed/27474374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2016.07.017 |
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