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Reducing Multifunctional Adsorption to Improve Recovery and In Vivo Detection of Neuropeptides by Microdialysis with LC-MS

Neuropeptides are an important class of neurochemicals; however, measuring their concentration in vivo by using microdialysis sampling is challenging due to their low concentration and the small samples generated. Capillary liquid chromatography with mass spectrometry (cLC-MS) can yield attomole lim...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Zhou, Ying, Wong, Jenny-Marie, Mabrouk, Omar S., Kennedy, Robert T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118035/
https://ncbi.nlm.nih.gov/pubmed/26351736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b02086
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