Ancestry-based stratified analysis of Immunochip data identifies novel associations with celiac disease

To identify candidate genes in celiac disease (CD), we reanalyzed the whole Immunochip CD cohort using a different approach that clusters individuals based on immunoancestry prior to disease association analysis, rather than by geographical origin. We detected 636 new associated SNPs (P<7.02 × 10...

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Bibliografiske detaljer
Udgivet i:Eur J Hum Genet
Main Authors: Garcia-Etxebarria, Koldo, Jauregi-Miguel, Amaia, Romero-Garmendia, Irati, Plaza-Izurieta, Leticia, Legarda, Maria, Irastorza, Iñaki, Bilbao, Jose Ramon
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Short Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117923/
https://ncbi.nlm.nih.gov/pubmed/27650971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2016.120
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