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Comparison of bile salt/phosphatidylcholine mixed micelles in solubilization to sterols and stability
Androst-3β,5α,6β-triol (Triol) is a promising neuroprotective agent, but its poor solubility restricts its development into parenteral preparations. In this study, Triol is significantly solubilized by bile salt/phosphatidylcholine mixed micelles (BS/PC-MM). All BS/PC-MM systems are tested to remark...
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| Publié dans: | Drug Des Devel Ther |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Dove Medical Press
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5117881/ https://ncbi.nlm.nih.gov/pubmed/27895469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S119918 |
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