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Cholesterol attenuates cytoprotective effects of phosphatidylcholine against bile salts

Bile salts have potent detergent properties and damaging effects on cell membranes, leading to liver injury. However, the molecular mechanisms for the protection of hepatocytes against bile salts are not fully understood. In this study, we demonstrated that the cytotoxicity of nine human major bile...

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Publicat a:Sci Rep
Autors principals: Ikeda, Yoshito, Morita, Shin-ya, Terada, Tomohiro
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428433/
https://ncbi.nlm.nih.gov/pubmed/28331225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00476-2
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