Most of the tight positional conservation of transcription factor binding sites near the transcription start site reflects their co-localization within regulatory modules

BACKGROUND: Transcription factors (TFs) form complexes that bind regulatory modules (RMs) within DNA, to control specific sets of genes. Some transcription factor binding sites (TFBSs) near the transcription start site (TSS) display tight positional preferences relative to the TSS. Furthermore, near...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Acevedo-Luna, Natalia, Mariño-Ramírez, Leonardo, Halbert, Armand, Hansen, Ulla, Landsman, David, Spouge, John L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117513/
https://ncbi.nlm.nih.gov/pubmed/27871221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1354-5
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