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Most of the tight positional conservation of transcription factor binding sites near the transcription start site reflects their co-localization within regulatory modules

BACKGROUND: Transcription factors (TFs) form complexes that bind regulatory modules (RMs) within DNA, to control specific sets of genes. Some transcription factor binding sites (TFBSs) near the transcription start site (TSS) display tight positional preferences relative to the TSS. Furthermore, near...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Acevedo-Luna, Natalia, Mariño-Ramírez, Leonardo, Halbert, Armand, Hansen, Ulla, Landsman, David, Spouge, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117513/
https://ncbi.nlm.nih.gov/pubmed/27871221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1354-5
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