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Acid sphingomyelinase is required for cell surface presentation of Met receptor tyrosine kinase in cancer cells
Receptor tyrosine kinases (RTKs) are embedded in the lipid bilayer of the plasma membrane, but the specific roles of various lipids in cell signaling remain largely uncharacterized. We have previously found that acid sphingomyelinase (ASM; also known as SMPD1) regulates the conserved DAF-2 (the orth...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5117200/ https://ncbi.nlm.nih.gov/pubmed/27802163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.191684 |
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