Cocaine-induced reduction of brain neuropeptide Y synthesis dependent on medial prefrontal cortex.

Repeated administration of cocaine elicits substantial, long-lasting, but reversible reductions in neuropeptide Y (NPY) and NPY mRNA in the rat cerebral cortex and nucleus accumbens. The NPY reduction appears to be mediated through a decrease in NPY biosynthesis, occurring transneuronally, perhaps i...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Wahlestedt, C, Karoum, F, Jaskiw, G, Wyatt, R J, Larhammar, D, Ekman, R, Reis, D J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51172/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2006146/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.6.2078
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