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Genetic Ablation of Ca(V)3.2 Channels Enhances the Arterial Myogenic Response by Modulating the RyR-BK(Ca) Axis
OBJECTIVE: In resistance arteries, there is an emerging view that smooth muscle Ca(V)3.2 channels restrain arterial constriction through a feedback response involving the large-conductance Ca(2+)-activated K(+) channel (BK(Ca)). Here, we used wild-type and Ca(V)3.2 knockout (Ca(V)3.2(−/−)) mice to d...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5117108/ https://ncbi.nlm.nih.gov/pubmed/26069238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.305736 |
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