Expression of gp91phox and p22phox, catalytic subunits of NADPH oxidase, on microglia in Nasu-Hakola disease brains

The superoxide-producing nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex of phagocytes (phox) plays a key role in production of reactive oxygen species (ROS) by microglia. The catalytic subunits of the NADPH oxidase are composed of p22phox and gp91phox. Nasu-Hakola disease (NHD)...

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Udgivet i:Intractable Rare Dis Res
Main Authors: Satoh, Jun-ichi, Kino, Yoshihiro, Yanaizu, Motoaki, Tosaki, Youhei, Sakai, Kenji, Ishida, Tusyoshi, Saito, Yuko
Format: Artigo
Sprog:Inglês
Udgivet: International Research and Cooperation Association for Bio & Socio-Sciences Advancement 2016
Fag:
Brief Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116863/
https://ncbi.nlm.nih.gov/pubmed/27904823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5582/irdr.2016.01086
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