Importance of the C-terminal histidine residues of Helicobacter pylori GroES for Toll-like receptor 4 binding and interleukin-8 cytokine production

Helicobacter pylori infection is associated with the development of gastric and duodenal ulcers as well as gastric cancer. GroES of H. pylori (HpGroES) was previously identified as a gastric cancer-associated virulence factor. Our group showed that HpGroES induces interleukin-8 (IL-8) cytokine relea...

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Published in:Sci Rep
Main Authors: Lee, Haur, Su, Yu-Lin, Huang, Bo-Shih, Hsieh, Feng-Tse, Chang, Ya-Hui, Tzeng, Shiou-Ru, Hsu, Chun-Hua, Huang, Po-Tsang, Lou, Kuo-Long, Wang, Yeng-Tseng, Chow, Lu-Ping
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116745/
https://ncbi.nlm.nih.gov/pubmed/27869178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37367
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