Hypoxia-induced vasculogenic mimicry formation in human colorectal cancer cells: Involvement of HIF-1a, Claudin-4, and E-cadherin and Vimentin

Vasculogenic mimicry (VM) plays an important role in colorectal cancer (CRC) metastasis, and both hypoxia and the epithelial-mesenchymal transition (EMT) are necessary for VM. In this study, HIF-1α expression was upregulated in the VM-positive CRC cell line HCT-116 and thereby affected the expressio...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Li, Wen, Zong, ShaoQi, Shi, Qi, Li, HongJia, Xu, Jian, Hou, Fenggang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116622/
https://ncbi.nlm.nih.gov/pubmed/27869227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37534
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