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Possible therapeutic role of IgE blockade in irritable bowel syndrome
Omalizumab is a humanized monoclonal antibody that binds to the high-affinity type-I IgE Fc receptors on mast cells (MCs) and basophils, inhibiting the IgE immune pathway. Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder, and dysregulation of the immune system l...
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| Gepubliceerd in: | World J Gastroenterol |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Baishideng Publishing Group Inc
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5116590/ https://ncbi.nlm.nih.gov/pubmed/27920467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i43.9451 |
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