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Possible therapeutic role of IgE blockade in irritable bowel syndrome

Omalizumab is a humanized monoclonal antibody that binds to the high-affinity type-I IgE Fc receptors on mast cells (MCs) and basophils, inhibiting the IgE immune pathway. Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder, and dysregulation of the immune system l...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Magen, Eli, Chikovani, Tinatin
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116590/
https://ncbi.nlm.nih.gov/pubmed/27920467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i43.9451
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