Design, synthesis, and functional expression of a gene for charybdotoxin, a peptide blocker of K+ channels.
A gene encoding charybdotoxin (CTX), a K+ channel blocker from scorpion venom, was designed, synthesized, and expressed as a cleavable fusion protein in Escherichia coli. A sequence-specific protease, factor Xa, was used to cleave the fusion protein and thus release the toxin peptide. The recombinan...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51165/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1706515/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.6.2046 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|