A neuronal lactate uptake inhibitor slows recovery of extracellular ion concentration changes in the hippocampal CA3 region by affecting energy metabolism

Astrocyte-derived lactate supports pathologically enhanced neuronal metabolism, but its role under physiological conditions is still a matter of debate. Here, we determined the contribution of astrocytic neuronal lactate shuttle for maintenance of ion homeostasis and energy metabolism. We tested for...

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Vydáno v:J Neurophysiol
Hlavní autoři: Angamo, Eskedar Ayele, Rösner, Joerg, Liotta, Agustin, Kovács, Richard, Heinemann, Uwe
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2016
Témata:
Control of Homeostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116486/
https://ncbi.nlm.nih.gov/pubmed/27559140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00327.2016
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