DNA Damage Response and Autophagy: A Meaningful Partnership

Autophagy and the DNA damage response (DDR) are biological processes essential for cellular and organismal homeostasis. Herein, we summarize and discuss emerging evidence linking DDR to autophagy. We highlight published data suggesting that autophagy is activated by DNA damage and is required for se...

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Bibliographic Details
Published in:Front Genet
Main Authors: Eliopoulos, Aristides G., Havaki, Sophia, Gorgoulis, Vassilis G.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116470/
https://ncbi.nlm.nih.gov/pubmed/27917193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00204
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