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A comprehensive genome-wide analysis of melanoma Breslow thickness identifies interaction between CDC42 and SCIN genetic variants

Breslow thickness (BT) is a major prognostic factor of cutaneous melanoma (CM), the most fatal skin cancer. The genetic component of BT has only been explored by candidate gene studies with inconsistent results. Our objective was to uncover the genetic factors underlying BT using an hypothesis-free...

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Détails bibliographiques
Publié dans:Int J Cancer
Auteurs principaux: Vaysse, Amaury, Fang, Shenying, Brossard, Myriam, Wei, Qingyi, Chen, Wei V., Mohamdi, Hamida, Vincent-Fetita, Lynda, Margaritte-Jeannin, Patricia, Lavielle, Nolwenn, Maubec, Eve, Lathrop, Mark, Avril, Marie-Françoise, Amos, Christopher I., Lee, Jeffrey E., Demenais, Florence
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116391/
https://ncbi.nlm.nih.gov/pubmed/27347659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30245
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