Integrated pathway and epistasis analysis reveals interactive effect of genetic variants at TERF1 and AFAP1L2 loci on melanoma risk

Genome-wide association studies (GWASs) have characterized 13 loci associated with melanoma, which only account for a small part of melanoma risk. To identify new genes with too small an effect to be detected individually but which collectively influence melanoma risk and/or show interactive effects...

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Vydáno v:Int J Cancer
Hlavní autoři: Brossard, Myriam, Fang, Shenying, Vaysse, Amaury, Wei, Qingyi, Chen, Wei V., Mohamdi, Hamida, Maubec, Eve, Lavielle, Nolwenn, Galan, Pilar, Lathrop, Mark, Avril, Marie-Françoise, Lee, Jeffrey E., Amos, Christopher I., Demenais, Florence
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566921/
https://ncbi.nlm.nih.gov/pubmed/25892537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29570
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