Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production.

CD45, a hematopoietic cell-specific surface antigen, has recently been shown to be a protein tyrosine phosphatase. Expression of CD45 is essential for the T-cell antigen receptor to couple with the phosphatidylinositol second messenger pathway and for antigen-mediated proliferation of T lymphocytes....

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Detalles Bibliográficos
Main Authors: Koretzky, G A, Picus, J, Schultz, T, Weiss, A
Formato: Artigo
Idioma:Inglês
Publicado: 1991
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC51163/
https://ncbi.nlm.nih.gov/pubmed/1672451
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