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Activation of MAP-2 kinase activity by the CD2 receptor in Jurkat T cells can be reversed by CD45 phosphatase.

We have recently characterized a serine kinase in T lymphocytes which phosphorylates microtubule-associated protein-2 (MAP-2) in vitro. This kinase is activated in a rapidly reversible fashion during ligation of CD3/Ti by a process which involves tyrosine phosphorylation of the enzyme itself. We sho...

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Detalhes bibliográficos
Main Authors: Nel, A E, Ledbetter, J A, Williams, K, Ho, P, Akerley, B, Franklin, K, Katz, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1384454/
https://ncbi.nlm.nih.gov/pubmed/1676984
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