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Dynamic domains of amyloid fibrils can be site-specifically assigned with proton detected 3D NMR spectroscopy

Several amyloid fibrils have cores framed by highly dynamic, intrinsically disordered, domains that can play important roles for function and toxicity. To study these domains in detail using solid-state NMR spectroscopy, site-specific resonance assignments are required. Although the rapid dynamics o...

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Detalhes bibliográficos
Publicado no:J Biomol NMR
Main Authors: Falk, Alexander S., Siemer, Ansgar B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116245/
https://ncbi.nlm.nih.gov/pubmed/27766502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-016-0069-2
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