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Optimizing effect sizes with imaging enrichment and outcome choices for mild Alzheimer’s disease clinical trials
Recent clinical trials in mild Alzheimer’s disease (AD) have enriched for amyloid-specific positron emission tomography imaging and used extended versions of the AD Assessment Scale-Cognitive Subscale (ADAS-Cog) in an effort to increase the sensitivity to detect treatment effects. We used data from...
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Udgivet i: | Alzheimer Dis Assoc Disord |
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Main Authors: | , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2017
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5116001/ https://ncbi.nlm.nih.gov/pubmed/27196535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WAD.0000000000000150 |
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