The neuroinflammatory component of gray matter pathology in multiple sclerosis

OBJECTIVE: In multiple sclerosis (MS), using simultaneous magnetic resonance-positron emission tomography (MR-PET) imaging with (11)C-PBR28, we quantified expression of the 18kDa translocator protein (TSPO), a marker of activated microglia/macrophages, in cortex, cortical lesions, deep gray matter (...

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Udgivet i:Ann Neurol
Main Authors: Herranz, Elena, Giannì, Costanza, Louapre, Céline, Treaba, Constantina A., Govindarajan, Sindhuja T., Ouellette, Russell, Loggia, Marco L, Sloane, Jacob A., Madigan, Nancy, Izquierdo-Garcia, David, Ward, Noreen, Mangeat, Gabriel, Granberg, Tobias, Klawiter, Eric C., Catana, Ciprian, Hooker, Jacob M, Taylor, Norman, Ionete, Carolina, Kinkel, Revere P., Mainero, Caterina
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115951/
https://ncbi.nlm.nih.gov/pubmed/27686563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24791
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