Profiles of cortical inflammation in multiple sclerosis by (11)C-PBR28 MR-PET and 7 Tesla imaging

BACKGROUND. Neuroinflammation with microglia activation is thought to be closely related to cortical MS lesion pathogenesis. OBJECTIVE. Using (11)C-PBR28 and 7 Tesla (7T) imaging, we assessed in 9 RRMS and 10 SPMS patients 1) microglia activation in lesioned and normal appearing cortex, 2) cortical...

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Detalhes bibliográficos
Publicado no:Mult Scler
Main Authors: Herranz, Elena, Louapre, Celine, Treaba, Constantina Andrada, Govindarajan, Sindhuja T, Ouellette, Russell, Mangeat, Gabriel, Loggia, Marco L, Cohen-Adad, Julien, Klawiter, Eric C., Sloane, Jacob A., Mainero, Caterina
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994367/
https://ncbi.nlm.nih.gov/pubmed/31368404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1352458519867320
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