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Haploinsufficiency of the Myc regulator Mtbp extends survival and delays tumor development in aging mice

Alterations of specific genes can modulate aging. Myc, a transcription factor that regulates the expression of many genes involved in critical cellular functions was shown to have a role in controlling longevity. Decreased expression of Myc inhibited many of the deleterious effects of aging and incr...

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Библиографические подробности
Опубликовано в: :Aging (Albany NY)
Главные авторы: Grieb, Brian C., Boyd, Kelli, Mitra, Ramkrishna, Eischen, Christine M.
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115908/
https://ncbi.nlm.nih.gov/pubmed/27803394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101092
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