Structure of the STRA6 receptor for retinol uptake

Vitamin A homeostasis is critical to normal cellular function. Retinol-binding protein (RBP) is the sole specific carrier in the bloodstream for hydrophobic retinol, the main form in which vitamin A is transported. The integral membrane receptor STRA6 mediates cellular uptake of vitamin A by recogni...

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Published in:Science
Main Authors: Chen, Yunting, Clarke, Oliver B., Kim, Jonathan, Stowe, Sean, Kim, Youn-Kyung, Assur, Zahra, Cavalier, Michael, Godoy-Ruiz, Raquel, von Alpen, Desiree C., Manzini, Chiara, Blaner, William S., Frank, Joachim, Quadro, Loredana, Weber, David J., Shapiro, Lawrence, Hendrickson, Wayne A., Mancia, Filippo
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114850/
https://ncbi.nlm.nih.gov/pubmed/27563101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad8266
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