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A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenance
RAP1 is one of the components of shelterin, the capping complex at chromosome ends or telomeres, although its role in telomere length maintenance and protection has remained elusive. RAP1 also binds subtelomeric repeats and along chromosome arms, where it regulates gene expression and has been shown...
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| Publicado en: | Aging Cell |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5114719/ https://ncbi.nlm.nih.gov/pubmed/27586969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12517 |
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