In vivo protein interaction network analysis reveals porin-localized antibiotic inactivation in Acinetobacter baumannii strain AB5075

The nosocomial pathogen Acinetobacter baumannii is a frequent cause of hospital-acquired infections worldwide and is a challenge for treatment due to its evolved resistance to antibiotics, including carbapenems. Here, to gain insight on A. baumannii antibiotic resistance mechanisms, we analyse the p...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Wu, Xia, Chavez, Juan D., Schweppe, Devin K., Zheng, Chunxiang, Weisbrod, Chad R., Eng, Jimmy K., Murali, Ananya, Lee, Samuel A., Ramage, Elizabeth, Gallagher, Larry A., Kulasekara, Hemantha D., Edrozo, Mauna E., Kamischke, Cassandra N., Brittnacher, Mitchell J., Miller, Samuel I., Singh, Pradeep K., Manoil, Colin, Bruce, James E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114622/
https://ncbi.nlm.nih.gov/pubmed/27834373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13414
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