Biocatalytic trifluoromethylation of unprotected phenols

Organofluorine compounds have become important building blocks for a broad range of advanced materials, polymers, agrochemicals, and increasingly for pharmaceuticals. Despite tremendous progress within the area of fluorination chemistry, methods for the direct introduction of fluoroalkyl-groups into...

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Udgivet i:Nat Commun
Main Authors: Simon, Robert C., Busto, Eduardo, Richter, Nina, Resch, Verena, Houk, Kendall N., Kroutil, Wolfgang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114620/
https://ncbi.nlm.nih.gov/pubmed/27834376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13323
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