GR-independent down-modulation on GM-CSF bone marrow-derived dendritic cells by the selective glucocorticoid receptor modulator Compound A

Dendritic cells (DC) initiate the adaptive immune response. Glucocorticoids (GCs) down-modulate the function of DC. Compound A (CpdA, (2-(4-acetoxyphenyl)-2-chloro-N-methyl-ethylammonium chloride) is a plant-derived GR-ligand with marked dissociative properties. We investigated the effects of CpdA o...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Barcala Tabarrozzi, Andres E., Andreone, Luz, Deckers, Julie, Castro, Carla N., Gimeno, María L., Ariolfo, Laura, Berguer, Paula M., Antunica-Noguerol, María, Liberman, Ana C., Vettorazzi, Sabine, Tuckermann, Jan P., De Bosscher, Karolien, Perone, Marcelo J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114550/
https://ncbi.nlm.nih.gov/pubmed/27857212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36646
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