The Role of PDGFR-β Activation in Acquired Resistance to IGF-1R Blockade in Preclinical Models of Rhabdomyosarcoma()

To determine what alternative pathways may act as mechanisms of bypass resistance to type 1 insulin-like growth factor receptor (IGF-1R) blockade in rhabdomyosarcoma (RMS), we compared expression of receptor tyrosine kinase activity in a number of IGF-1R antibody-resistant and -sensitive RMS cell li...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Transl Oncol
Prif Awduron: Heske, Christine M., Yeung, Choh, Mendoza, Arnulfo, Baumgart, Joshua T., Edessa, Leah D., Wan, Xiaolin, Helman, Lee J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press 2016
Pynciau:
Original article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114528/
https://ncbi.nlm.nih.gov/pubmed/27835791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2016.09.002
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