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Enhanced in utero allogeneic engraftment in mice after mobilizing fetal HSCs by α4β1/7 inhibition

In utero hematopoietic cell transplantation (IUHCT) is a novel nonmyeloablative approach that results in donor-specific tolerance and mixed allogeneic chimerism. Clinical application is limited by low levels of donor cell engraftment. Competition from endogenous hematopoietic stem cells (HSCs) for l...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Kim, Aimee G., Vrecenak, Jesse D., Boelig, Matthew M., Eissenberg, Linda, Rettig, Michael P., Riley, John S., Holt, Matthew S., Conner, Michael A., Loukogeorgakis, Stavros P., Li, Haiying, DiPersio, John F., Flake, Alan W., Peranteau, William H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114489/
https://ncbi.nlm.nih.gov/pubmed/27650329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-06-723981
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