Enhanced in utero allogeneic engraftment in mice after mobilizing fetal HSCs by α4β1/7 inhibition

In utero hematopoietic cell transplantation (IUHCT) is a novel nonmyeloablative approach that results in donor-specific tolerance and mixed allogeneic chimerism. Clinical application is limited by low levels of donor cell engraftment. Competition from endogenous hematopoietic stem cells (HSCs) for l...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Kim, Aimee G., Vrecenak, Jesse D., Boelig, Matthew M., Eissenberg, Linda, Rettig, Michael P., Riley, John S., Holt, Matthew S., Conner, Michael A., Loukogeorgakis, Stavros P., Li, Haiying, DiPersio, John F., Flake, Alan W., Peranteau, William H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114489/
https://ncbi.nlm.nih.gov/pubmed/27650329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-06-723981
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